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Interleukin-21: a double-edged sword with therapeutic potential

Moreover, omega-3 fatty acids have anti-inflammatory effects on microglial cells because the resolving, one of the metabolites of omega-3 fatty acids, inhibits the production of inflammatory cytokines

Moreover, L-Carnitine suppressed genes responsible for protein degradation in skeletal muscle [17] and decreased muscle RING-finger protein-1 ( MuRF1 ) and ubiquitin-protein conjugates, involved in protein catabolism, as well as increases the levels of IGF-1 and Akt1, two upstream elements in the mammalian target of rapamycin (mTOR), the main driver of protein anabolism [18]

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