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Adv Nutr 8(3):511519 Locatelli JC, Costa JG, Haynes A, Naylor LH, Fegan PG, Yeap BB et al (2024) Incretin-Based weight loss pharmacotherapy: can resistance exercise optimize changes in body composition

Graphical Abstract Similar content being viewed by others Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), with a steady upward trend in prevalence estimates from 25.3% in 19902006 to 38.2% in 20162019 [1], has become a leading cause of chronic liver disease worldwide [2,3,4], increasing the risk of both hepatic and extrahepatic complications, such as cardiovascular and chronic kidney diseases [5, 6]

Many patients see steady, sustainable reductions in body weight

Its unique architecture allows for a coordinated metabolic response that is frequently studied for its potential to surpass the efficacy of dual agonists like Tirzepatide