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Long-Term Results: Six Months and Beyond Clinical trials demonstrate that sustained use of GLP-1 medications over twelve to eighteen months can produce average weight loss of fifteen to twenty percent of starting body weight

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These medications work through distinct mechanisms: DPP-4s slow the breakdown of incretin hormones, while GLP-1 agonists directly activate GLP-1 receptors

The dose of NAC was chosen according to our published studies ( gpx1 / + NAC group compared with the peroxynitrite + gpx1 / group (Figure 6B)