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Researchers employed Propensity Score Matching to rigorously control for all known confounders, including diabetes, obesity, and hypertension

Within a few years, the downtown area, which previously offered only a few saloons and hotels, became populated with banks, fancier hotels, and a range of sophisticated shops

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The accumulation of toxic substances leads to oxidative damage to cells and a decrease in Na + -K + -ATPase activity, which results in the activation of NMDA receptors, neuronal depolarization, and clinical symptoms such as seizures