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In OA, however, due to an inflammatory microenvironment and cellular stress, glycolytic flux often becomes further elevated to meet energy demands, while mitochondrial dysfunction may reduce oxidative phosphorylation efficiency (100)

Peptide Therapy may not be suitable for individuals with certain medical conditions, including: Pregnant or breastfeeding women Severe allergies to peptides Uncontrolled diabetes or certain hormone imbalances Its important to consult with your healthcare provider to determine if Peptide Therapy is right for you based on your health history

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Chetan Gadgil for carefully reviewing our manuscript and for useful discussions