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Existing Therapies and Analogues: Successful drugs in the field of diabetes (primarily T2D), such as GLP-1 receptor agonists (e.g., semaglutide) and SGLT2 inhibitors (e.g., empagliflozin), have shown benefits in both lowering blood glucose and aiding weight loss

However, frail elderly patients and those over 80 years are often underrepresented in clinical trials, meaning real-world clinical judgement is paramount

Foundayo, a newer oral GLP-1, offers flexibility in dosing without meal constraints, and Zepbound, a dual GIP/GLP-1 agonist, combines two hormonal targets for enhanced results