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Astrocytes can function as secretory cells, releasing a variety of signaling moleculesincluding classical neurotransmitters (ATP, GABA, glutamate and glycine), gliotransmitters (D-serine and glycine), metabolic substrates (lactate) and growth factors (BDNF and TGF-)through exocytic vesicles, transporters or channels

Mohammed, I., Hollenberg, M

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Those who feel stimulated by NAD+ tend to keep NAD in the morning and reserve evenings for glutathione plus sleep-supportive options such as melatonin nasal spray or theanine nasal spray GABA