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10.1016/j.lfs.2021.119622 Life Sci

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315 The expression levels of GLP-1R, PKA/CREB signaling pathway components, and inflammation-related proteins (such as TNF-, IL-1, and IL-6) in the rat knee cartilage tissue were measured using Western blot and immunoprecipitation techniques

Body weight, glucose tolerance, and the glycemic response to semaglutide were similar in Glp1r Tie2+/+ and Glp1r Tie2/ male (Figure 3, AC) and female mice (Supplemental Figure 5, AC)