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After repeated administration, rats in the short-access paradigm exhibited lower daily and cumulative METH intake than saline controls, with this effect becoming apparent on the second day of treatment and continuing throughout the study, while LIR did not affect METH-taking behavior in the extended-access paradigm

Once reconstituted, it follows the same strict 28C storage requirements as semaglutide, insulin, and other therapeutic peptides used in clinical settings.

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