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The researchers reported that liraglutide at 10 to 100 nM significantly inhibited ASC proliferation and viability (45% and 50% inhibition at 10 nM and 100 nM after 6 days of culture), with the effect reversed by the GLP-1R antagonist exendin 9-39 (confirming receptor-mediated action)

Compared to conventional lipo-based vesicles and manufactured nanoparticles, exosomes are more biocompatible and readily absorbed by target cells due to their membrane proteins and endogenous origin

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