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However, due to the potency of prescription-grade ingredients like Tretinoin and NAD+, it may not be suitable for: People with rosacea or active eczema/psoriasis flares Those with extremely sensitive or compromised skin barriers Anyone who is pregnant or breastfeeding Individuals allergic to retinoids, copper peptides, or any formula component If you're unsure, we recommend consulting with your provider before beginning use

Source peptides from trusted providers, consult a clinician of good repute, monitor for side effects, and refrain when contraindicated

Up to 75% of adults will experience hemorrhoids by age 50, with pregnancy, chronic constipation, and prolonged sitting increasing risk due to increased pressure on anal veins

In vitro and experimental animal models have been favourable, however, limited clinical evidence exists