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The neurotoxicity of IFN- is well established (298), as well as the cognitive impairment induced by this cytokine (299)

In terms of LDL-C lowering, rosuvastatin has proven most effective, whilst pravastatin and simvastatin are better for increasing HDL-C, and atorvastatin in reducing triglyceride levels [31, 32] (Figure 1)

So I think that what were missing in the whole discussion is thinking about how do we ramp up mitochondrial energy production, how do we prevent it from declining and aging so that the body, so that the brain can rightly perceive that I am in a state of abundance