GLP-1 RAs induce an increase in heart rate (HR), which, theoretically, represents a safety concern, as this is considered to be associated with higher cardiovascular risk [13, 14]
1 Introduction Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by impaired hypothalamic development and function with an estimated incidence of 1 per 20,000 newborns ( Patients with PWS experience complex nutritional, neurodevelopmental, metabolic and behavioral changes that drive obesity development ( Obesity management in PWS typically includes a calorie-restricted diet, strict control of food access, regular physical activity and behavioral interventions ( 2 Case series 2.1 Patient 1 A 28-year-old female with PWS, resulting from uniparental disomy, was evaluated at our Endocrinology Unit
These results will reassure patients and physicians caring for them, and support doctors in choosing the most appropriate drug without consideration of possible differences in the risk of retinopathy complications. This article was developed by the editorial staff in conjunction with experts in the field
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