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Clinical trials show it is as safe and effective in non-diabetics as it is in those with diabetes, with comparable tolerability profiles

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However, another 205-patient RCT reported that, although a minority of patients did experience an ALT rise with 4 g paracetamol daily, this rise resolved following further days of dosing [25]

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By improving insulin secretion, reducing glucagon levels, and slowing gastric emptying, semaglutide can significantly improve blood sugar control

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