The OFA argued that the FDAs removal of tirzepatide, the active ingredient in these drugs, from its shortage list would limit access to essential treatments and increase drug prices
Altmed gives patients a local place to ask questions when side effects, insurance delays, prescription availability, or health changes come up
In a mouse model relevant to myalgic encephalomyelitis/chronic fatigue syndrome rather than FM, combined lipopolysaccharide administration and swim stress activated the diencephalic NLRP3 inflammasome, leading to caspase-1-mediated IL-1 maturation and fatigue-like motor deficits, while lactate and MDA levels remained unchanged
This dysbiosis is driven by multiple factors, including intestinal urea accumulation, impaired ammonia metabolism secondary to renal dysfunction, dietary modifications, and medical interventions ( Figure 2 ) [35, 111]