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Another complication could be that altering the capacity of a single antioxidative enzyme may produce indirect effects on ROS availability that then alter the flux through other pathways that oxidize GSH, thus masking more direct effects

Recent studies have shown that people diagnosed with this type of disorder have significantly lower levels of glutathione

Glutathione may be responsible for several vital roles within a cell besides antioxidation: Maintenance of the redox state (chemical reactions in which the oxidation state of atoms are modified) Modulation of the immune response Detoxification of foreign bacteria and viruses Glutathione and chronic disease: Research has demonstrated that Glutathione deficiency may be a factor in many chronic conditions

Low-pH preparation of skeletal muscle satellite cells can be used to study activation in vitro