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Oridonin, a diterpenoid compound isolated from Rabdosia rubescens , was shown to alleviate PI-IBS symptoms in rats by significantly inhibiting phosphorylation of NF-B p65 and downregulating downstream inflammatory mediators such as inducible nitric oxide synthase (iNOS), COX-2, IL-1, and IL-6

It can promote tissue repair, reduces inflammation, enhances angiogenesis (new blood vessel formation), and remains stable in gastric juice enabling effective oral administration

Finally, dietary glutamine increased the number of IgA-secreting B cells in the small intestine of young mice (156) and enhanced intestinal levels of IgA in various weaning animals (157161)

Regular use can help to reduce the bodys toxins load