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Nature 624 , 164172 (2023)

Without adequate copper availability at the follicular level, newly synthesized collagen structures remain weak and fail to provide the structural support necessary for robust hair growth

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The essence of PCOS is a heterogenous presentation of androgen excess (which appears as hyperandrogenism, hirsutism, acne, alopecia, and seborrhoea), ovulatory dysfunction (which appears as oligo-ovulation, menstrual dysfunction, and subfertility) and polycystic ovarian morphology (PCOM)