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Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation

What can go wrong Pain, swelling and a small lump The most common outcome of a rushed or badly angled injection is local irritation: soreness, redness, a small firm lump or a bruise

Here are the signs of a B12 deficiency: Extreme tiredness Lack of energy Memory, understanding, and judgment issues Mouth ulcers Muscle weakness Psychological problems like depression or confusion Tongue redness and swelling The body doesnt naturally produce vitamin B12, so its crucial to treat the deficiency with a B12 shot as soon as possible if your diet doesnt give you your daily recommended dose.

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