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American journal of physiology Regulatory, integrative and comparative physiology

Preparation and in vivo evaluation of a topical hydrogel system incorporating highly skin-permeable growth factors, quercetin, and oxygen carriers for enhanced diabetic wound-healing therapy

The authors have investigated three treatments to correct metabolic abnormalities which have demonstrated improvement in behavior and/or metabolism, namely the combination of methylcobalamin (mB12) with low-dose folinic acid (LDFA) to treat oxidative stress in an open-label study (James et al., 1A demonstrates where these agents are believed to act within four major interconnected metabolic pathways that are known to be disrupted in ASD