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In Proceedings of the IEEE International Conference on Computer Vision (ICCV), pp

Variants in gut immunity-related genes (such as NOD2) may indirectly regulate the intestinal toxicity of MPs by altering microbiota composition and modulating the intensity of inflammatory signals

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On top of understanding the microbial pathogenesis and the molecular and cellular mechanisms of disease biology, activity of a therapeutic agent in a translational research, be it either in vitro or in vivo, is critical to proffer advancement to first-in-human clinical trials based on laboratory findings of pharmacology, toxicology, and immunology