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SeeramNPAronsonWJZhangYHenningSMMoroALeeRPet al

Some authors posit that long-term Selank use may cause desensitization of the GABAergic system, resulting in increased anxiety, depression, insomnia, and related issues

For runners, thats a dangerous trade-off. The appetite suppression inherent in the medications can also make it difficult to meet your caloric needs, especially during high training loads