The findings from this post hoc analysis of SUSTAIN 6 and PIONEER 6 reinforce the recommendation in the guidelines that GLP-1RAs should be used to reduce the risk of MACE across the spectrum of age, and offer an alternative approach to treatment de-escalation, as is currently advised by the ADA in adults 65 years [6], which should lead to better outcomes for older adults [1, 18, 22]
This can lead to injection site reactions, such as redness, swelling, itching, or pain
Unfortunately, once a pen has been stored at room temperature, it should remain at room temperature and be used within 28 days
This is because each additional week on semaglutide gives your GLP-1 receptors more time to adapt, and adaptation is cumulative even at lower doses