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A decline in the cellular GSH level is indicative of an ethanol-induced oxidative stress, which is characterized by the generation of toxic acetaldehyde and other reactive molecules in the cell

All the reactions were operated under a nitrogen atmosphere using a Schlenk-line system and a glovebox to protect air- and moisture-sensitive chemicals

The drops must stay under the tongue long enough for significant quantities to cross the membrane

GPX4 requirements in vivo are not consistent across macrophage subsets and are limited to alternatively activated macrophages whose proliferation or expansion is reduced after GPX4 deletion [78]