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Warfarin and other anticoagulants in line with GLP-1 RA SmPCs (e.g., semaglutide), more frequent INR monitoring is advisable when starting retatrutide or changing the dose, as any alteration in gastric motility could affect anticoagulant control

An observational cohort study involving 168 pregnant women exposed to GLP-1 receptor agonists during the first trimester found a 2.6% prevalence of major birth defects, comparable to 2.3% in the diabetic reference group

For many individuals, adding their medication to an existing morning ritual ensures they never forget a dose