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Because GLP-1 medications naturally reduce appetite and slow digestion, people often eat less overall

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GLP-1 has been reported to improve glucose-dependent insulin action through the G-protein-coupled receptor, GLP-1R ( GLP-1 is involved in the regulation of energy balance (Holst, 2007), and its activation and subsequent binding to the GLP-1R reduces food intake and, consequently, body weight (Turton et al., 1996)