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Pregnancy and lactation safety has not been systematically studied, and as with most cosmetic and research compounds lacking definitive pregnancy safety data, conservative practice typically suggests avoiding use during pregnancy unless clearly needed, though the natural occurrence of GHK-Cu in the body and minimal systemic absorption from topical use suggest risk is likely to be low

The clinical features of AGHD includes abnormal body composition, decreased cardiac capacity, increased risk of fracture, insulin resistance, and decreased quality of life

Its origins in gastric juice foreshadowed its profound ability to maintain gut integrity and orchestrate complex repair processes

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