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doi: 10.3892/ijmm.2013.1252 8

The dosing structures are fundamentally different because each peptide has a different receptor profile, different potency per milligram, and different pharmacokinetic properties

The Mayo Clinic's guidance on GLP-1 medications also emphasizes gradual dose titration to improve tolerability

Despite likely being a similar tier as GLP-1 RAs and SGLT2is for many patient insurances, this elevated AWP is important to note for patients with co-insurances, deductibles, the Medicare coverage gap, patients without insurance, and for the total cost of healthcare