Giblin, F.J., Glutathione: a vital lens antioxidant
Inhibition of PGC-1 expression has been shown to result in decreased expression of the mitochondrial fusion protein Mfn2, increased expression of p-Drp1, and increased mitochondrial fragmentation (Guo et al., 2015)
FDA-approved Semaglutide is an analog of one such gut hormone called glucagon-like peptide-1 (GLP-1), a multifaceted hormone with broad pharmacological potential [that exerts] numerous metabolic effects [such as] glucose-dependent stimulation of insulin secretion, decrease of gastric emptying, inhibition of food intake, increase of natriuresis and diuresis, and modulation of -cell proliferation. Hormone replacement therapy (HRT) can help you get off that treadmill to nowhere and start making real, sustainable weight loss progress
Where each stands and what the data shows The reported results put them in a rough order on efficacy, though cross-trial comparisons are not definitive
