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10.1007/s00415-022-11304-7 27 VazquezM.FagiolinoP.MaldonadoC.OlmosI.IbarraM.AlvarizaS.et al (2014)

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5-Amino-1MQ is a small molecule that inhibits the NNMT enzyme to boost NAD+ levels, while MOTS-c is a mitochondrial peptide that activates the AMPK pathway, mimicking exercise