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Molecular mechanisms turned out to be complicated for several reasons: A single OR can activate simultaneously different signaling pathways such ACase, MAP kinases or ion channels and it is possible to observe different levels of desensitization when considering those cellular responses

Meyer, C

It also engages ERK1/2 signaling, facilitates endothelial and muscle repair, and exerts anti-inflammatory effects

Its more likely another underlying issue, like iron deficiency, medications or hypothyroidism, causes brittle nails, but biotin can help improve the condition. What we do know is that eating foods with biotin assists the enzymes that break down fats, carbs and proteins in your food