differences between semaglutide and tirzepatide vs. Ozempic: Comparing Diabetes Treatments & Weight Loss Benefits Semaglutide vs Tirzepatide: Which Is

Qi L, Gao R, Chen Z, Lin D, Liu Z, Wang L, et al

Key results at 80 weeks: Participants on the 4 mg dose lost an average of 47.2 lbs (19.0%) Participants on the 12 mg dose lost an average of 70.3 lbs (28.3%) 45.3% of participants on the 12 mg dose achieved at least 30% weight loss a level historically associated with bariatric surgery outcomes The 4 mg dose showed a lower rate of discontinuation due to adverse events than even placebo In a study extension to 104 weeks, participants with a starting BMI of 35 or higher who received 12 mg lost up to an average of 85.0 lbs (30.3%)

Transparent regulatory positioning

Novo Nordisk's patent for Saxenda expires later this year, and rivals Teva, Pfizer and Mylan are all expected to launch generic versions of liraglutide later in 2024