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NTZ has been reported to modulate UPR signaling, promoting antioxidant defenses, suppressing inflammatory cytokines, inhibiting PDI, and ultimately preventing cell injury (Di Santo and Ehrisman, 2014

It protects liver, lung, and cardiac tissues from fibrosis and oxidative stress, as demonstrated in models of acute lung injury and cardiotoxicity

Our results also showed that GHK itself is not toxic and does not induce the change of irritancy/sensitizing related biomarkers, which provides an additional benefit when used for complexation with copper

doi: 10.4049/jimmunol.2101056 159 Barrientos-RobledoSGCebada-RuizJARodriguez-AlbaJCBaltierra-UribeSLDiazYOMARomero-RamirezH