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GLP-1 medications typically produce greater triglyceride reductions (10-25%) compared to LDL changes (variable 5-15%)

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This marks the second BLA for SC Entyvio under FDA review, as the regulator accepted a BLA resubmission for the formulation for maintenance therapy in adults with moderately to severely active ulcerative colitis after IV Entyvio induction therapy in April 2023

It is possible that improvement in nerve size following GLP-1 RA treatment may be due to augmentation of pump activity and normalisation of the sodium electrochemical gradient, as suggested by previous human and animal studies [7]