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46 KrainzT.GaschlerM

Beyond the established roles of short-chain fatty acids (SCFAs) and bile acids, recent findings reveal that branched-chain amino acids, trimethylamine N-oxide, tryptophan and indole derivatives, have been implicated in the pathogenesis of metabolic disorders ( 2.2 Immunomodulatory coordination The gut microbiota plays a crucial role in maintaining immune homeostasis

Of those 161 patients, 16 (10%) experienced recurrent acute pancreatitis after GLP-1 receptor agonist therapy (mean duration 10.8 7.2 months): 6 (38%) were caused by the GLP-1 receptor agonist (as clinically determined by the treating medical team), three (18%) were due to hypertriglyceridemia, two (12%) due to alcohol use, one (6%) due to another oral hypoglycemic agent, one (6%) due to ampulla stenosis, and three (19%) were idiopathic

Increasing treatment time resulted in additional by-products, which could not be identified