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At the early stage of prediabetes, the OGTT results demonstrated that the insulin exhaustion appeared in the second phase of insulin release

Additionally, mitochondrial stress may disrupt Ca + homeostasis, activate the mitochondrial permeability transition pore (mPTP), and facilitates the efflux of mitochondrial matrix Ca + , leading to mitochondrial swelling, outer membrane rupture, and subsequent dysfunction (6062)

NAC in infertility Sperm function is susceptible to oxidative stress too much severely impairs the ability of sperm to swim while also causing defects in the precious DNA cargo ( 11 )

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