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No, semaglutide does not directly cause headaches, but they may occur as a result of other side effects

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Benefits include: \Musculoskeletal Repair: May support faster healing of tendons, ligaments, muscle, and bone (Animal Study)

2019 Mar 1;102(2):395-411

My best guess is some sort of activation of the RAAS system is happening to lower blood pressure along with the increase in urination seen with GLP-1 medications