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As an example of its mechanism of action, SAMe supplementation was shown to inhibit DNA demethylase, DNMT1 activity, and demethylation of PS1, a prime gene product involved in amyloidogenesis [143], as discovered in transgenic AD mice

10.1016/j.ebiom.2017.09.013 404 SocaaK.DoboszewskaU.SzopaA.SerefkoA.WodarczykM.ZieliskaA.et al

With Wellstars support, Social Cascade will help participating groups: Boost patient acquisition and engagement : Social Cascades platform will enable clinics to reach their patients more effectively, offering real-time advice, resources and support that align with their healthcare journeys

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