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Grieco M, Giorgi A, Gentile MC, dErme M, Morano S, Maras B, Filardi T (2019) Glucagon-Like Peptide-1: A Focus on Neurodegenerative Diseases

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Tanimoto K., Hizuka N., Fukuda I., Takano K., Hanafusa T

In addition, pathophysiological processes include both excitotoxicity of VPA metabolites and a decrease in gene transcription due to a decrease in the level of histone acetylation, which is accompanied by a loss of GABAergic (gamma-aminobutyric acid) neurons in the striatum as a pathological hallmark of Huntingtons disease [13,104]