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The severity of symptoms can also differ

Jutten LH, Mark RE, Wicherts JM, Sitskoorn MM

Modern clinical research has shown that saffron supplementation (typically 2050mg per day) can improve visual acuity, retinal function, and contrast sensitivity in adults with AMD.58 These effects are attributed to compounds called crocin and crocetin, which may enhance retinal blood flow and protect photoreceptor cells from oxidative stress

Besides animal studies, clinical investigations with humans have demonstrated beneficial effects of anserine on their metabolic, neurological, immunological, cardiovascular and renal functions