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The maximum weight reduction effect ranged from 4.25 kg (Liraglutide) to 22.6 kg (Retatrutide)

The Bottom Line In under two decades, GLP-1 agonists moved from niche diabetes drugs to pillars of cardiometabolic carelowering glucose, reducing weight, and, as SELECT showed, preventing heart attacks

Benito J, Shi Y, Szymanska B, Carol H, Boehm I, Lu H, Konoplev S, Fang W, Kornblau SM, Zweidler-McKay P, Wilson W, Campana D, Borthakur G, Bueso-Ramos CE, Kantarjian HM, Shpall EJ, Thomas DA, Jordan CT, Lock RB, Andreeff M , Konopleva M

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