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And the high NeuraLN group predominantly demonstrates the following biological functions:ACTIVATION_OF_IMMUNE_RESPONSE,ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY,B_CELL_ACTIVATION,DEFENSE_RESPONSE_TO_BACTERIUM,IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY,NEUTROPHIL_CHEMOTAXIS.These functions highlight the group's significant involvement in the immune response.Combined with these results, it was suggested that the high NeuraLN group was mainly involved in immune activation, and LN patients with this NeuraLN would be more likely to benefit from immunotherapy

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Epub 2017 Dec 28