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We thank commenters for their suggestion to cap hospitals in the lowest quartile of Safety of Care at no more than 2 stars or prohibiting 4- or 5-star ratings altogether to prevent these hospitals from being categorized as average or above average in overall quality

This represents a pharmaceutical design strategy of creating selectivity through structural modification, providing therapeutic benefits while minimizing unwanted effects

If your reading is below 4.0 mmol/L, treat the hypoglycaemia immediately with 1520 grams of fast-acting carbohydrate (such as glucose tablets, fruit juice, or sugary sweets), then recheck after 15 minutes

An increased risk of developing diabetes with EGRIFTA (HbA1c level 6.5%) relative to placebo was observed [intent-to-treat hazard odds ratio of 3.3 (CI 1.4, 9.6)]