do you build a tolerance to glp 1 GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists endogenous GLP-1 production and L-cell differentiation | Diabetology & Metabolic Syndrome The GLP-1 revolution: What UAB

10.1007/s11064-012-0775-4 32 ChechowskaM.GajewskaJ.SzczepanikE.MazurJ.CycholA.Kuniar-PakaA.et al (2025)

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Laboratory studies have also shown that GLP-1 receptor activation can reduce reward-seeking behaviors in models exposed to drugs or highly palatable foods, supporting the biological plausibility of these observations (2 Trusted Source The glucagon-like peptide-1 analogue exendin-4 decreases the rewarding value of food and drug rewards

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