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1 Infertility affects 1215% of couples in the United States

Free Radical Biol Med 152:175185 Vats K, Kruglov O, Mizes A, Samovich SN, Amoscato AA, Tyurin VA, Tyurina YY, Kagan VE, Bunimovich YL (2021) Keratinocyte death by ferroptosis initiates skin inflammation after uvb exposure

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The peptide's resistance to dipeptidyl peptidase-IV (DPP-IV) proteolysis is achieved through substitution of -methyl-Phe at position 2, which blocks the cleavage of the Tyr1Ala2 bond that normally inactivates native incretins within minutes of secretion