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These activated T cells then release pathogenic inflammatory cytokines, contributing to the development of autoimmune diseases (96)

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Methodologically, among the included longitudinal studies, only 9 were double blind RCTs, 11 were open-label RCTs and 4 were non-randomized observational studies

"Her GP gave her a course of 6 vitamin B12 injections" My understanding of UK guidance on treatment for B12 deficiency is that as neurological symptoms were present eg twitching, memory problems then the treatment should have continued beyond the 6 loading injections