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On the other spectrum, Mounjaro (Tirzepatide), the dual GLP-1 and GIP receptor agonist, has gained FDA approval for its effectiveness in improving blood sugar control in adults with type 2 diabetes, offering an advantage in the treatment landscape with its dual-action mechanism that also contributes to significant weight loss trials

Additionally, high 5-alpha reductase activity in facial follicles means the conversion to DHT happens aggressively even at moderate androgen levels

This can lead to Tirzepatide back pain and discomfort

12 A recent large population-based study provides evidence of an association between vulvovaginal atrophy and overall female sexual dysfunction and its subtypes (i.e., desire difficulty, arousal difficulty, and orgasm difficulty)