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The stomach, adipose tissue, bone, and pancreas all express GIP receptors, and these have also been found in the cerebral cortex, hippocampus, and olfactory bulb, among other parts of the brain [15, 16]

Metabolic Resistance Point GLP-1 therapy is most strategically introduced when patients exhibit metabolic adaptations that counteract behavioral interventions: Plateau Effect: GLP-1 should be considered when patients adhering to a caloric deficit and exercise program experience a weight plateau, indicating a reduction in Total Daily Energy Expenditure (TDEE) as a physiological defense

Clinical studies show that most people lose 510% of their starting body weight over a year when using Saxenda alongside diet and exercise

But it does not stop at the stomach