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Patients consistently had improved glycemic levels and multiple drugs, such as tirzepatide alone or semaglutide in combination with cagrilinitide, were highly effective at promoting weight management

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doi:10.1016/0014-5793(96)00895-2 294

If you feel great at 4mg and want to move faster, you can consider a 3-week block at the next dose instead of 4, but never skip a dose level entirely