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With increasing pollution, our skin cells react to the damage by producing free radicals that cause premature ageing, fine lines, and wrinkles in our skin

Testa et al., 2011

Additionally, GLP-1 receptor agonists (like semaglutide) have shown neuroprotective effects, Parulekar continued

8.2 Nasal delivery (systemic or CNS-Targeted) Nasal delivery offers noninvasive administration, relatively rapid absorption through the nasal mucosa (richly vascularized, thin epithelium), avoidance of GI degradation, and the potential for nose-to-brain delivery of CNS-targeted peptides via the olfactory and trigeminal nerve pathways